Pascoe Pascofemin is a homeopathic remedy to relieve symptoms associated with menopause, PMS, and other hormonal disturbances such as hot flashes, sleep disorders, bloating, mood swings, irritability, breast tenderness, abdominal pain, and headaches. It is suitable for adults and children 12 years and up and made with naturally sourced medicinal ingredients including Agnus castus, Pulsatilla, Lilium tigrinum, and Cimicifuga.

Pascofemin Drops include the ingredient Fraxinus Americana. This key ingredient is widely used to help treat symptoms typically associated with menopause, such as hot flashes and mood changes. As well, it is also widely used to help treat uterine fibroids. The other active ingredients work to help relieve menstrual problems and other hormonal disturbances. The oral drops should be taken diluted in a little water.

Homeopathic remedy used to relieve symptoms associated with menopause PMS and other hormonal disturbances such as:

• hot flashes
• sleep disorders
• bloating
• mood swings
• irritability
• breast tenderness
• abdominal pain and headaches

Each tablet contains:
Agnus castus 2X 0.2g, cimicifuga 3X 0.2g, aletris farinosa 3X 0.075g, pulsatilla 4X 0.075g, heliconias dioica 3X 0.075g, lilium tigrinum 3X 0.075g, Ignatia 4X 0.075g, senecio aureus 5X 0.075g, caulophyllum 2X 0.075g and fraxinus americana 3X 0.075g. Contains 34% vol. alcohol.

NPN: 80026945

Once a dreaded phase of life, menopause is now regarded as an empowering passage—a time when all a woman has experienced and learned comes to fruition. No longer seen as merely the end of fertility, menopause is finally being recognized for what it actually brings—a phase of life that is ripe with freedom and opportunity.

Many of Nature’s plants and fungi are noted both scientifically and anecdotally for helping ease the transition through menopause. Not all are effective, and some—such as soy—have been linked to dangerous mutations. All ingredients in Purica® REBALANCE Menopause Relief have been carefully assessed, to ensure you derive maximum benefit, at minimal risk.

• Help control hot flashes and night sweats
• Help prevent mood swings
• Enhance youthfulness of skin, hair and nails
• Ameliorate stress
• Enhance libido
• Help prevent vaginal dryness
• Sop annoying skin itch/tingling (paresthesia)
• Encourage restful sleep
• Increase energy

Homeopathic remedy used to relieve symptoms associated with menopause PMS and other hormonal disturbances such as:

• hot flashes
• sleep disorders
• bloating
• mood swings
• irritability
• breast tenderness
• abdominal pain and headaches

For many women, the transition from pre- to post-menopause can be arduous. Changing hormone levels can lead to increased risk for both heart disease and osteoporosis, while inducing uncomfortable shorter-term issues such as vasomotor symptoms (hot flushes, night sweats), insomnia, vaginal dryness, mood changes, and reduction in libido.

MenoVantage PE is a potent formulation of botanicals and nutrients at clinically relevant doses for reducing peri-menopausal symptoms. Black cohosh (Actaea racemosa) is one of the most studied botanical extracts for menopausal symptom relief. Randomized double-blinded trials have shown a reduction in climacteric symptoms without an estrogenic effect when a standardized extract is used. Chasteberry (Vitex agnus-castus) extract is well known for modulating FSH/LH levels and mitigating premenstrual symptoms, and holds promise for reducing menopausal symptoms as well, particularly difficulty sleeping. Dong Quai (Angelica sinensis) has a long history of use in traditional medicine for reducing menopausal symptoms.

The traditional botanicals found in MenoVantage PE are complemented by gamma-oryzanol, derived from rice bran. This natural substance has been found not only to reduce menopausal symptoms in 85% of participants, but also to improve cardiovascular risk factors, including LDL-cholesterol, a concern for many perimenopausal women. Hesperidin, a citrus bioflavonoid derived from oranges, provides relief for vasomotor symptoms of menopause, as well as potent anti-inflammatory and metabolic benefits.

• Dong Quai Extract (Angelica sinensis) (root) 100 mg
• Chasteberry Extract (Vitex agnus-castus) (fruit) 80 mg
• Black Cohosh Extract (Actaea racemosa) (root, rhizome) 80 mg
• (2.5% Triterpene Glycosides as 27-deoxyactein)
• Gamma-Oryzanol (Oryza sativa) (seed bran) 75 mg
• Hesperidin (Citrus sinensis) (fruit) 30 mg

Non-Medicinal Ingredients:
Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

2 capsules at breakfast and 2 capsules at bedtime per day or as directed by a health care practitioner. Use for a minimum of 3 months to see beneficial effect. Consult a health care practitioner for use beyond 6 months.

Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Consult a health care practitioner if symptoms persist or worsen. Consult a health care practitioner prior to use if you have a family history of cancer, have a liver disorder or develop symptoms of liver trouble, if you are taking blood thinners/anticoagulants, hormone-containing medications such as progesterone preparations, oral contraceptives or hormone replacement therapy, if you are taking any prescription medications or are breastfeeding. Discontinue use and consult a health care practitioner if you experience breast pain, discomfort and/or tenderness, increased menstrual bleeding time or if menstruation is delayed or absent. Do not use if you have diarrhea, haemorrhagic diseases, hypermenorrhea/profuse menstrual flow/heavy periods, allergy/hypersensitivity to members of the Apiaceae/Umbelliferae family (anise, caraway, carrot, celery, dill parsley), or if you are pregnant. Keep out of reach of children.

Do not use if you are using anticoagulant/antiplatelet medications (warfarin; Ticlid). As black cohosh may interact with CYP2E1 and CYP2D6 substrates, practitioners should be aware of potential drug interactions. The use of vitex is contraindicated in conjunction with bromocriptine, metaclopramide, dopamine agonists and antipsychotic drugs.

Vaginal dryness has many possible causes and can lead to discomfort, itching, and pain to those afflicted, sometimes severely enough to impact daily life.

Hyaluronic acid is made naturally by our bodies. Our groundbreaking Vaginal Moisturizer Gel, compounded especially for the Menopause Chicks community by our own Pure Pharmacy pharmacists, is made with pure hyaluronic acid and vitamin E to restore moisture and repair damaged skin.

Studies show that hyaluronic acid moisturizers are equivalent in effectivity to hormonal treatments (1). As it's non-prescription, patients can also take control of their own treatment, adjusting the frequency of application to meet their specific needs.

1. Chen J, Geng L, Song X, Li H, Giordan N, Liao Q. Evaluation of the Efficacy and Safety of Hyaluronic Acid Vaginal Gel to Ease Vaginal Dryness: A Multicenter, Randomized, Controlled, Open‐Label, Parallel‐Group, Clinical Trial. The Journal of Sexual Medicine. 2013;10(6):1575-1584.

• No prescription needed - use as much or as little as you need!
• Contains hyaluronic acid and vitamin E
• Our robust air-tight pump bottle delivers a precise 0.5 gram dose with each press, preventing contamination and quality loss from oxydization and keeping the product fresh for as long as possible
• Free of dyes, ethanol, gluten, parabens, and propylene glycol

• 30gm: 2+ months
• 60gm: 4+ months (not recommended for best product quality)
• 90gm: 6+ months (not recommended for best product quality)

• 30gm: 1+ months
• 60gm: 2+ months
• 90gm: 3+ months

• 30gm: 15+ days
• 60gm: 1+ months
• 90gm: 1.5+ months

May increase vaginal discharge upon first starting. Amount of discharge often decreases after first 2 weeks. It is recommended to try the product for at least 3 weeks before deciding to discontinue. In rare cases, some patients may experience burning/irritation when using a vaginal product. If this occurs, and is not mild, please discontinue use.

Maca (Lepidium meyenii), a plant native to Peru, is a cruciferous, mineral-rich plant whose roots are eaten as a vegetable by the indigenous peoples. Maca balances the effects of major steroid hormones such as estrogen, progesterone, and testosterone, and seems to create effects that are specific to the condition of the individual, elevating low levels of some hormones while lowering levels of hormones present in excess. Health professionals who use Maca in their practices thus report that Maca assists in the maintenance of sexual function in aging men and women, and can be helpful in normalizing menopausal and premenstrual symptoms in women.

As an adaptogen (a substance that helps the body adapt to stress), Maca has been shown to support bone structure, fight stress, increase energy, and promote balanced blood glucose levels and cardiovascular health.

NPN: 80042647

• A Peruvian root traditionally used as an adaptogen
• Supports sexual function & psychological wellbeing for men and women
• Helps relieve menopausal symptoms and balance hormone levels
• Socially & ecologically responsible harvesting

Lepidium meyenii (Maca) root extract - 750 mg

Non-medicinal Ingredients:
microcrystalline cellulose, maltodextrin, sodium stearyl fumarate. Capsule: hypromellose.

Fem Adapt is AOR’s premium menopause formula that is especially useful for hot flashes. While many formulas on the market contain ingredients with minimal research in menopausal women, doses that are too low or unstandardized botanical extracts, Fem Adapt provides the most powerful, clinically studied, standardized phytoestrogens in research-backed doses. Fem Adapt contains flax lignans, soy isoflavones, black cohosh and a standardized hops extract, which collectively can reduce the severity and frequency of hot flashes and other menopausal concerns.

AOR’s Fem Adapt formula not only provides safe and effective relief from menopausal symptoms, but also provides protection against health problems for which the risk increases after menopause, such as cardiovascular complications, osteoporosis and others. This is due to the mild estrogenic activity of the phytoestrogens in the product, which can serve as natural hormone replacement therapy.

Additionally, some of the ingredients in Fem Adapt have been used in herbal medicine to help relieve premenstrual symptoms, including abdominal cramps, muscle and joint pain, nerve pain like sciatica and nervous tension.

NPN: 80034694

• Helps reduce hot flashes and night sweats while also promoting mood balance
• Helps balance hormones, reducing the risk of post-menopausal diseases
• Provides four of the most effective and research-backed phytoestrogen

Linum usitatissimum L. extract (Flax seed)168 mg
Soy Isoflavone extract 60 mg
— Total isoflavones18.2 – 27.4 mg AIE
Black Cohosh extract80 mg
LIFENOL Hops extract 120 mg

Non-medicinal Ingredients:
Microcrystalline cellulose, silicon dioxide, maltodextrin and tricalcium phosphate.

Consult a health care practitioner prior to use if you are breastfeeding, taking blood thinners, have a history of hormonal or gynecological disease including ovarian cancer, endometriosis or uterine fibroids, have a liver disorder or develop liver-related symptomsn (e.g. abdominal pain, jaundice, dark urine), are taking hormone replacement therapy (HRT) including thyroid hormone replacement therapy or have depression or related diseases. Discontinue use and consult a health care practitioner if you experience breast pain, discomfort or tenderness or if you experience a recurrence of menstruation and/or uterine spotting.

Consumption with alcohol, other medications or natural health products with sedative properties is not recommended. Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Hypersensitivity such as an allergy has been known to occur in rare cases, in which case discontinue use. Consult a health care practitioner if symptoms persist or worsen, or for use beyond one year.  This product contains corn and soy derived ingredients, do not use if you have such allergies.

Douglas Estro-Mend is a soy-free blend of herbs used in herbal medicine that helps ease nervous tension while relieving pain associated with menstruation and symptoms associated with menopause.

A complex interaction of hormones regulates menstruation. Imbalances of hormones, including estrogen, can result in menstrual pain and premenstrual symptoms, which often include changes in mood, energy, attention, appetite, sleep, physical comfort (breast tenderness, bloating) and quality of life. Phytoestrogens, including black cohosh, mimic the functions of estrogens without proliferative actions and help relieve menstrual pain and premenstrual symptoms.

Significantly less estrogen is produced in the period before menopause. Hormonal fluctuations during this time can result in common menopausal symptoms, including hot flushes and vaginal dryness. Phytoestrogens also support and minimize the changes and symptoms that are sometimes experienced during menopause. Studies have found that black cohosh helps relieve menopausal symptoms, such as hot flushes, excessive sweating, insomnia, and vaginal atrophy. As menopause may result in sleep disruption, Estro-Mend also contains hops, which can relieve nervousness and aid sleep.

NPN: 80040917

• Used in herbal medicine to help relieve premenstrual symptoms and pain associated with menstruation and helps to relieve symptoms associated with menopause

PMS Support contains a combination of ingredients including BioResponse DIM^®, magnesium, iron and B vitamins. It also contains chasteberry to help relieve menstrual symptoms and stabilize menstrual cycle irregularities. Premenstrual symptoms affect approximately 40% of women and may be associated with elevated levels of the hormone prolactin. Chasteberry extract (Vitex agnus-castus) is used in Herbal Medicine as a hormone normaliser and to help relieve menstrual symptoms. It contains active constituents that play a role in hormone activity, including dopaminergic compounds that suppress the release of prolactin. Studies have shown that chasteberry extract supplementation helps relieve premenstrual symptoms, including mood, headache, bloating, and breast fullness.

Diindolymethane (DIM) is a natural component derived from indole-3-carbinole and cruciferous vegetables. BioResponse DIM is the only form with proven absorption demonstrated in independently performed clinical studies.

Iron supplementation is helpful in menstruating women to support the maintenance of good health. PMS Support provides a carbonyl form of iron that is bioavailable and well tolerated. Magnesium has been noted to fluctuate across the menstrual cycle and is involved in many cellular pathways. It helps to maintain proper muscle function by decreasing cramping. B vitamins are also included to help promote energy production.

NPN: 80063027

• Premenstrual symptoms
• Menopause

Vitamin D3 (cholecalciferol) 12.5 mcg (500 IU/ UI)
Thiamine (thiamine hydrochloride) 12.5 mg
Vitamin B6 (pyridoxal 5'-phosphate) 9.5 mg
Folate (calcium L-5-methyltetrahydrofolate) 200 mcg
Ferronyl ®MD Iron (carbonyl iron) 9 mg
Magnesium (magnesium chelate√) 100 mg
BioResponse DIM®50 mg Providing 12.5 mg
Chaste Berry Fruit Extract (Vitex agnus-castus) (7-10:1) (350-500 mg dried equivalent) 50 mg

Non-medicinal ingredients:
Hypromellose (capsule), cellulose, magnesium stearate, silica, starch, vitamin E, phosphatidylcholine (from sunflower)

Adults: Take 1 capsule 2 times daily with food, a few hours before or after taking other medications or natural health products, or as directed by your healthcare practitioner. Use for a minimum of 3 months to see beneficial effects

Do not use if pregnant or breastfeeding. Consult your healthcare practitioner prior to use if you are attempting to conceive, have a liver disorder or symptoms of low estrogen, are taking hormone-containing medications such as progesterone preparations, oral contraceptives, hormone replacement therapy, other medications or natural health products.

Discontinue use and consult your healthcare practitioner if you develop liver-related symptoms or symptoms of low estrogen. Folate supplementation can mask vitamin B12 Consult your healthcare practitioner prior to use if unsure whether you are taking enough vitamin B12. Consult your healthcare practitioner if symptoms persist or worsen. Use only if safety seal in intact. Store in a cool, dry place

• Relief for Menopausal Mood Changes

Motherwort (Leonurus cardiaca) 4:1 aerial parts extract equivalent to 400 mg of motherwort 100 mg
Black Cohosh (Actaea racemosa) root & rhizome extract 80 mg
Lemon Balm (Melissa officinalis) 4:1 leaf extract equivalent to 200 mg of lemon balm 50 mg

Take one tablet twice daily or as directed by your healthcare practitioner.

Consult your healthcare practitioner before use

• Formulated to provide support for women with menopausal symptoms such as hot flushes, insomnia, low mood, decreased libido and poor cognition
• Herbal extracts are highly concentrated with standardization to active ingredients such as ligustilides, 27-deoxyactein and hypericin
• Quercetin and hesperidin are included to improve the integrity of blood vessels and reduce hot flashes

Dong Quai extract (Angelica sinensis) 5:1, 1% ligustilides 60mg
Black cohosh extract (root and rhizome, Actaea racemosa) 3:1, 2.5% triterpene glycosides 50mg
Hesperidin 125mg
Quercetin 125mg
Chasteberry extract (fruit, Vitex agnus-castus) 10:1 50mg
Wild yam extract (root, Dioscorea villosa) 10:1 50mg
St. John’s Wort extract (herb top, Hypericum perforatum) 4:1, 0.3% hypericin 30mg
Red clover extract (flower, Trifolium pratense) 10:1 20mg

Non-Medicinal Ingredients:
Vegetable-grade magnesium stearate, microcrystalline cellulose, maltodextrin, silicon dioxide. Capsule: hypromellose.

Adults - Take 2 capsules 2 times per day before meals or as directed by a healthcare professional.

Do not use if safety seal is broken. Discontinue use and consult a healthcare professional if menstruation is delayed or absent, or if you experience increased menstrual bleeding time. Consult a healthcare professional prior to use, especially if you have a family history of cancer, a liver disorder or develop symptoms of liver trouble, or if you are taking any prescription medications, anti-anxiety medications, seizure medications, antihistamines, bronchodilators, muscle relaxants and/or opiates, hormone-containing medications such as progesterone preparations, oral contraceptives, birth control pills or hormone replacement therapy. Consult a healthcare professional if symptoms persist or worsen. Avoid prolonged exposure to sunlight, ultraviolet light (UV) or UV therapy.

Contraindications: Do not use if you are pregnant, breastfeeding or taking anti-cancer medications, blood thinners/antidepressants medications (e.g selective serotonin reuptake inhibitors (SSRI), anti-HIV agents, cardiovascular medications, immunosuppressants, and/or contraceptive medications. Do not use if you have diarrhoea, haemorrhagic diseases, hypermenorrhoea/profuse menstrual flow/heavy periods, or allergy/hypersensitivity to members of the Apiaceae/Umbelliferae family (anise, caraway, carrot, celery, dill, parsley).

An evidence-based blend of herbs and nutrients to increase endogenous progesterone, support fertility and encourage a healthy menstrual cycle.

NPN: 80090621

• Indicated for improving health concerns associated with low progesterone levels in women, including premenstrual syndrome, irregular menstrual cycles, polycystic ovarian syndrome, peri-menopause, hyperprolactinemia, insomnia and infertility
• Provides a highly concentrated 10:1 extract of Vitex agnus-castus with vitamin C and a mixed tocopherol blend, sourced from GMO-free rapeseed oil, to support healthy progesterone levels
• Pyridoxal-5-phosphate (P-5-P), the biologically active form of vitamin B6, is added for the efficient conversion of 5-HTP into serotonin and the production of other neurotransmitters

Mixed tocopherol concentrate 89mg
Vitamin B6 (pyridoxal-5-phosphate) 12.5 mg
Vitamin C (ascorbic acid) 187.5 mg
Chasteberry extract (fruit, Vitex agnus-castus) 10:1 50mg

Non-Medicinal Ingredients:
Vegetable-grade magnesium stearate, microcrystalline cellulose, rice hull powder, tapioca starch. Capsule: hypromellose.

Adults - Take 1 capsule, 2 times per day or as directed by a healthcare professional.

Do not use if safety seal is broken. Consult a health care professional prior to use, especially if you are taking hormone-containing medications such as progesterone preparations, oral contraceptives, birth control pills or hormone replacement therapy. Consult a healthcare professional if symptoms persist or worsen.

Vitex or Chaste tree is a traditional woman’s dietary supplement. Vitex is widely used to promote overall health and balance in a woman’s cycle.

Evening primrose is native to North America. Originally used for the treatment of asthma, stomach and digestive disorders, and bruises, there is renewed interest in the herb because of the oil in this plant. Approximately 70% of the oil is cis-linoleic acid, and as much as 9% cis-gamma-linolenic acid (GLA). The oil also contains campestrol and beta-sitosterol. GLA is an essential polyunsaturated fatty acid that the body converts to a hormone-like substance called prostaglandin E1 (PGE1). PGE1 has anti-inflammatory properties and may also act as a blood thinner and blood-vessel dilator. The anti-inflammatory properties of EPO have been studied in double-blind research with people suffering from rheumatoid arthritis. Some, but not all, studies have reported that EPO supplementation provides significant benefits to these people. GLA, the primary active ingredient in EPO, has anticancer activity in test-tube experiments. Primrose oil has been used to treat the symptoms associated with premenstrual syndrome: irritability, headaches, breast tenderness, and bloating; it has also been helpful in the treatment of eczema. There are claims that increased doses help rheumatoid arthritis and slow the progression of multiple sclerosis.
Linoleic acid, a common fatty acid found in nuts, seeds, and most vegetable oils (including EPO), should theoretically convert to PGE1, but many things can interfere with this conversion, including disease, the aging process, saturated fats, hydrogenated oils, blood-sugar problems, and inadequate amounts of vitamin C, magnesium, zinc, and B vitamins. Supplements that provide GLA circumvent these conversion problems, leading to a more predictable formation of PGE1.
Despite the fact that most over-the-counter pain relievers and many prescription arthritis medicines work primarily by blocking prostaglandin synthesis, prostaglandins do play an important role in many biochemical reactions. Very few plants contain GLA in any significant quantity.
EPO is often used for premenstrual syndrome, allergies and bronchial asthma, high blood cholesterol, skin conditions (such as acne, eczema, and psoriasis), autoimmune conditions (multiple sclerosis, lupus, rheumatoid arthritis, and scleroderma), obesity, diabetes mellitus, and immune system depression.
Evening Primrose Oil is available in 500 mg or 1000 mg softgels. Most of the clinical trials have administered doses of 1–2 softgels two or three times daily, with a maximum adult dose of 4 g daily. In some conditions, up to three months may be needed to see a response.

RepaGyn® is a hormone-free option to help relieve vaginal dryness and help promote healing of vaginal tissue

*We are only able to ship this item to Canadian customers.

NPN: 80039889

Medicinal ingredients:
Each 2 g vaginal ovule contains 5 mg of Sodium Hyaluronate.

Non-medicinal ingredients:
Aloe vera, Centella Asiatica, Calendula officinalis, Tea tree essential oil, Semi-synthetic glycerides, Butylated hydroxytoluene (BHT)

Place one ovule into the vagina daily, preferably at bedtime, for at least two or three weeks. In the case of vaginal atrophy, RepaGyn® vaginal suppositories may be used even for longer periods.
The duration of use depends on the evolution of symptoms and on the advice of your healthcare practitioner.

Interactions with other products are not known; therefore it is advisable to consult a healthcare practitioner before using RepaGyn® in association with other vaginal products. Do not use if pregnant or breastfeeding.

Consult a healthcare practitioner if symptoms persist or worsen. Keep the product out of reach and sight of children. Avoid contact with eyes. Do not swallow.

Replens Long-Lasting Vaginal Moisturizer provides immediate alleviation of dryness symptoms and helps replenish vaginal moisture. Simply apply Replens a couple of times a week to help alleviate the feminine discomfort associated with vaginal dryness.

Replens is different from other lotions or lubricants because it contains a patented bio-adhesive ingredient that allows it to attach to dry cells and deliver continuous moisture. Replens leaves vaginal tissues hydrated and feeling rejuvenated.

*We are only able to ship this item to Canadian customers.

DIN:

• Lasts up to 3 days
• Fragrance-free
• Compatible with most condoms (natural rubber latex, polyisoprene, and polyurethane)

Aqua, Glycerin, Paraffinum, Liquidum, Polycarbophil, Carbomer, Homopolymer Type B, Hydrogenated Palm Glyceride, Sorbic Acid, Sodium Hydroxide.

• Remove the cap from the REPLENSTM tube. Break the seal on tube opening by puncturing it with the opposite end of the cap. Screw the open end of the applicator onto the tube. 
• Gently squeeze the tube, pushing the REPLENSTM into the open barrel of the applicator. DO NOT roll up the tube. The applicator contains the recommended amount when the plunger stops (approximately a cm).
• Unscrew the applicator from the tube. Replace the cap.
• While sitting, standing, or lying on your back with knees bent, gently insert the open end of the applicator into the vagina as deeply as it will go comfortably. Holding the applicator in place with thumb and middle finger, press the plunger until it stops. Withdraw the applicator
• Immediately after use, pull the plunger all the way out of the barrel and wash both parts of the applicator in warm, soapy water. Rinse thoroughly and dry. The applicator should be completely dry before reassembly. To reassemble, gently push the plunger back into the barrel as far as it will go.
• REPLENSTM coats the vaginal mucosa to provide long-lasting moisturization and lubrication.

Store at room temperature (15-30°C.) Avoid exposure to extreme heat or cold. REPLENS is not a contraceptive. Keep out of reach of children. If pregnant or breast feeding, consult your healthcare provider before use.